Probing the Radiation-Induced Changes of Extravascular Extracellular Space of Parotid Glands using DCE and DW MRI
نویسندگان
چکیده
C-C. Cheng, C-J. Juan, H-W. Chung, Y-M. Jen, H-C. Chang, S-C. Chiu, C-Y. Chen, C-J. Hsueh, Y-S. Lin, and G-S. Huang Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan, Department of Radiology, Tri-Service General Hospital, Taipei, Taiwan, Department of Radiation Oncology, Tri-Service General Hospital, Taipei, Taiwan, Applied Science Laboratory, GE Healthcare, Taipei, Taiwan, Department of Otorhinolaryngology-Head and Neck Surgery, Tri-Service General Hospital, Taipei, Taiwan
منابع مشابه
Positional changes in parotid glands during head and neck radiation therapy
Introduction: Xerostomia is the most common complication due to radiation–induced damage to salivary glands in head and neck cancer radiotherapy and it reduces quality of life. Parotid glands are main glands which they are account for secretion of stimulated saliva. Studies have demonstrated that mean tolerance parotid’s radiation dose under 26-30 Gy result in an increase in t...
متن کاملQuantitative assessment of salivary gland function by radioisotopic scanning in a randomized trial of Pilocarpine for prevention of radiation induced Xerostomia [Persian]
Introduction: Radioisotope scanning is the best method for objective assessment of salivary gland function. Thus, it was used in a randomized trial of concomitant pilocarpine for assessment of radiation-induced xerostomia, in addition to subjective evaluation by an approved questionnaire and objective standard xerostomia grading. Methods: Patients randomized in placebo-controlled trial of...
متن کاملCombining DCE-MRI and microbubble ultrasound to evaluate response to Sunitinib in patients with renal cell carcinoma
INTRODUCTION: As more anti-angiogenic drugs are developed, assessment of patient response during therapy is becoming crucial. DCE-MRI has been proposed as a way of detecting changes in the vasculature. For example, the Tofts model (1) provides the volume transfer constant, Ktrans, which describes permeability and flow, and ve, the extravascular, extracellular volume fraction. It has been shown ...
متن کاملDynamic Contrast Magnetic Resonance Imaging (DCE-MRI) and Diffusion Weighted MR Imaging (DWI) for Differentiation between Benign and Malignant Salivary Gland Tumors
Background: Salivary gland tumors form nearly 3% of head and neck tumors. Due to their large histological variety and vicinity to facial nerves, pre-operative diagnosis and differentiation of benign and malignant parotid tumors are a major challenge for radiologists. Objective: The majority of these tumors are benign; however, sometimes they tend to transform into a malignant form. Functional M...
متن کاملComparison of DCE-MRI and Dual Echo DSC-MRI Derived Measures of K and ve
Introduction: DSC-MRI data from tumors may be confounded by the extravasation of contrast agent (CA) into the extravascular extracellular space (EES), which results in simultaneous changes in the EES T1 and T2*. It is well known that dual-echo acquisitions can eliminate the T1 leakage effects, but we recently demonstrated that such data, when combined with a pre-contrast T1 map, can also be use...
متن کامل